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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Microb Pathog. 2019 Dec 24;140:103942. doi: 10.1016/j.micpath.2019.103942

Table 2.

Impact of the mycobiome on infection and disease.

Mycobiome Prevalent fungi Associated diseases and reference (s)
Gut Candida
Cladosporium
Malassezia
Saccharomyces
Crohn’s disease, irritable bowel syndrome, ulcerative colitis [Hager and Ghannoum, 2017; Mar Rodriguez et al., 2015]
Lung Ascomycota
Basidiomycota
Asthma, chronic obstructive pulmonary disorder, cystic fibrosis, HIV [Tipton et al., 2017; Willger et al., 2014; Harrison et al., 2013; Cui et al., 2015; Krause et al., 2016]
Oral Aspergillus
Candida spp.
Epicoccum
Malassezia
HIV, periodontal disease [Ghannoum et al., 2010; Dupuy et al., 2014; Monteiro-da-Silva et al., 2014; Zakaria et al., 2017; Peters et al., 2017; Mukherjee et al., 2014]
Vaginal/Urinary tract Candida spp. Bacterial vaginosis, intra-uterine device associated infections, urinary tract infection [Drell et al., 2013; Srinivasan et al., 2012; Goldacre et al., 1979; Ackerman and Underhill, 2017; Bradford and Ravel, 2017]
Skin Malassezia Atopic dermatitis, atopic eczema, dandruff, folliculitis, psoriasis [Kong and Morris, 2017; Zhang et al., 2011; Gaitanis et al., 2012; Kato et al., 2007; Sugita et al., 2003; Chang et al., 2011; Park et al., 2012; McGinley et al., 1975]
Nails Trichophyton
rubrum
Aspergillus spp.
Candida spp.
Onychomycosis [Veer and Damle, 2007; Kotwal, 2018; Yang, et al., 2011; Foster et al., 2005]