Table 1. Immunosuppressive agents associated with the development of Pneumocystis pneumonia.
| Immunosuppressive agent | |
|---|---|
| Corticosteroids | mTOR inhibitors |
| Alkylating agents | Everolimus |
| Cyclophosphamide | Sirolimus |
| Temozolomide | Temsirolimus |
| Antibiotics/Immunosuppressants | TNF-α inhibitors |
| Bleomycin | Adalimumab |
| Antimetabolites | Certolizumab pegol |
| Cytarabine | Etanercept |
| Fluorouracil | Golimumab |
| Methotrexate | Infliximab |
| Calcineurin inhibitors | IL-6 inhibitors |
| Cyclosporine | Sarilumab |
| Tacrolimus | Tocilizumab |
| Purine analogs | Monoclonal antibodies |
| Azathioprine | Alemtuzumab |
| Cladribine | Rituximab |
| Fludarabine | JAK inhibitor |
| Mycophenolate mofetil | Tofacitinib |
| CTLA4-Ig* | |
| Belatacept | |
*CTLA4-Ig: fusion protein composed of the extracellular domain of cytotoxic T-lymphocyte antigen 4 (CTLA-4).
mTOR: mammalian target of rapamycin; TNF-α: tumor necrosis factor α; IL-6: interleukin 6.