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. 2020 Mar 30;11(3):207. doi: 10.1038/s41419-020-2388-1

Fig. 3. Subgroup analysis of EFS by CAR-T therapy in R/R B-ALL patients (statistically significant).

Fig. 3

Better EFS was observed in patients with non-refractory disease compared with patients with refractory disease (a), in patients with blast <5% compared with patients with blast ≥5% (b), in patients with other lymphodepletion regimens compared with patients with Flu + Cy regimen (c), as well as in patients bridged to HSCT compared with patients with CAR-T therapy only (d). Kaplan–Meier curve was used to demonstrate survival profiles, and the log-rank test was used to determine the difference between paired subgroups. P < 0.05 was considered significant. EFS, event-free survival; Flu + Cy, cyclophosphamide plus fludarabine; HSCT, hematopoietic stem-cell transplantation; CAR-T, chimeric antigen-specific T cell.