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. 2020 Feb 19;17(2):209–222. doi: 10.1007/s13770-020-00239-7

Table 2.

Glucose effects on DBMSC expression of oxidative genes with pro-oxidant and antioxidant properties. DBMSCs were untreated (DBMSC) or treated with 200 mM glucose (TDBMSC) for 72 h

# Gene symbol Gene full name DBMSC
Mean ΔΔ−2 values
TDBMSC
Mean ΔΔ−2 values
Fold change (TDBMSC vs. DBMSC)
p < 0.05
Biological properties
1 NOX2 (CYBB) Cytochrome b-245, β polypeptide 1 11.62 11.62 fold Pro-oxidant property
2 NOX4 NADPH oxidase 4 1 9.89 > 9 fold
3 NOX5 NADPH oxidase 5 1 14 14 fold
4 DUOX1 Dual oxidase 1 1 2 2 fold
5 DUOX2 Dual oxidase 2 1 52 52 fold
6 NCF1 Neutrophil cytosolic factor 1 1 6.59 6.59 fold
7 NCF2 Neutrophil cytosolic factor 2 1 50 50 fold
8 ALOX12 Arachidonate 12-lipoxygenase 1 519 519 fold
9 AOX1 Aldehyde oxidase 1 1 34 34 fold
10 GPX1 Glutathione peroxidase 1 1 0.10 10 fold Anti-oxidant property
11 GPX5 Glutathione peroxidase 5 1 13 13 fold
12 GPX6 Glutathione peroxidase 6 1 0.02 50 fold
13 PRDX2 Peroxiredoxin 2 1 0.02 50 fold
14 PRDX3 Peroxiredoxin 3 1 0.39 > 2.50 fold
15 CAT Catalase 1 0.56 > 1.70 fold
16 SOD1 Superoxide dismutase 1 1 0.016 > 62 fold
17 SOD2 Superoxide dismutase 2 1 0.052 > 19 fold
18 TTN Titin 1 0.20 5 fold