Table 5.
Glucose effects on DBMSC expression of oxidative genes. DBMSCs were untreated (DBMSC) or treated with 200 mM glucose (TDBMSC) for 72 h
| # | Gene symbol | Gene full name | DBMSC Mean ΔΔ−2 values |
TDBMSC Mean ΔΔ−2 values |
Fold change (TDBMSC vs. DBMSC) |
|---|---|---|---|---|---|
| 1 | EPX | Eosinophil peroxidase | 1 | 1.09 | Fold Change is not statistically significant, p > 0.05 |
| 2 | APOE | Apolipoprotein E | 1 | 1.26 | |
| 3 | TXNRD1 | Thioredoxin reductase 1 | 1 | 0.74 | |
| 4 | EPHX2 | Epoxide hydrolase 2, cytoplasmic | 1 | 0.81 | |
| 5 | APOE | Apolipoprotein E | 1 | 1.26 | |
| 6 | GCLM | Glutamate-cysteine ligase, modifier subunit | 1 | 0.88 | |
| 7 | GPX1 | Glutathione peroxidase 1 | 1 | 0.10 | |
| 8 | FTH1 | Ferritin, heavy polypeptide 1 | 1 | 0.62 | |
| 9 | EPX | Eosinophil peroxidase | 1 | 1.09 | |
| 10 | MSRA | Methionine sulfoxide reductase A | 1 | 0.71 | |
| 11 | OXSR1 | Oxidative-stress responsive 1 | 1 | 0.88 | |
| 12 | RNF7 | Ring finger protein 7 | 1 | 0.61 | |
| 13 | SCARA3 | Scavenger receptor class A, member 3 | 1 | 0.79 | |
| 14 | SQSTM1 | Sequestosome 1 | 1 | 0.65 | |
| 15 | NUDT1 | Nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 1 | 0.37 | |
| 16 | SRXN1 | Sulfiredoxin | 1 | 1.72 | |
| 17 | PREX1 | Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | 1 | 1.59 | |
| 18 | CCS | Copper chaperone for superoxide dismutase | 1 | 0.65 | |
| 19 | DHCR24 | 24-dehydrocholesterol reductase | 1 | 1.40 | |
| 20 | GCLC | Glutamate-cysteine ligase, catalytic subunit | 1 | 1.90 | |
| 21 | GSS | Glutathione synthetase | 1 | 1.89 | |
| 22 | MPV17 | MpV17 mitochondrial inner membrane protein | 1 | 1.68 | |
| 23 | ATOX1 | ATX1 antioxidant protein 1 homolog (yeast) | 1 | 1.86 | |
| 24 | CCL5 | Chemokine (C–C motif) ligand 5 | 1 | 0.67 | |
| 25 | MPO | Myeloperoxidase | 1 | 1.58 |