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Nanovesicles reduced the production of pro-inflammatory cytokines. HCAECs were pretreated with NV or FT/NV for 2 h. Then, cells were incubated with TNF-α for 6 h. The mRNA expression levels of A IL-1β, B TNF-α, C IL-6, and D IL-8 were determined by real-time qPCR. Data are mean ± SD from 3 independent experiments. ***p < 0.001
