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. 2020 Mar 24;8:183. doi: 10.3389/fcell.2020.00183

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Copyright © 2020 Khoshdel Rad, Aghdami and Moghadasali.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Major genetic markers involved in kidney development. The cell fate decision of renal cells are coordinately controlled with different genetic markers during nephrogenesis. AIM, anterior intermediate mesoderm; AQP, aquaporin; BMP, bone morphogenetic protein; Brn1, Bruno-like1; CALB1, calbindin; CD, Collecting duct; CM, cap mesenchyme; CSB, comma-shaped body; EMX, empty spiracles homolog; Eya1, eyes absent 1; FGF, fibroblast growth factor; FOXi1, forkhead box protein i1; FRS2α, fibroblast growth factor receptor substrate 2α; GATA, trans-acting T-cell-specific transcription factor; GDNF, glial cell–derived neurotrophic factor; GFRα1, glial cell line derived neurotrophic factor family receptor α1; Jag1, Jagged 1; HOX, homeobox; IM, intermediate mesoderm; Kdr, kinase insert domain protein receptor; LHX1, LIM-class homeodomain 1; LTL, lotus tetragonolobus lectin; MM, metanephric mesenchyme; NPCs, nephron progenitor cells; NPHS1, nephrosis 1; Osr1, odd skipped related 1; PAX, paired box protein; PI3K, phosphoinositide 3-kinases; PIM, posterior intermediate mesoderm; PTA, pre-tubular aggregate; RV, renal vesicle; SIX2, sine oculis-related homeobox 2; SLC2614, solute carrier 2614; SSB, S-shaped body; SYNPO, synaptopodin; TGFβ, transforming growth factor beta; UB, ureteric bud; UMOD, uromodulin; WNT, wingless-type mouse mammary tumor virus integration site; WD, Wolffian duct.