Table 2.

Diseases under categories of nephrotic syndrome (NPHS) and focal segmental glomerulosclerosis (FSGS) in the Online Mendelian Inheritance in Man (OMIM)

Disease	Gene	Inheritance	OMIM numbera	Proteins
NPHS1	NPHS1	AR	256300	Nephrin
NPHS2	PDCN	AR	600995	Podocin
NPHS3	PLCE1	AR	610725	Phospholipase c, epsilon-1
NPHS4	WT1	AD	256370	WT1 transcription factor
NPHS5	LAMB2	AR	614199	Laminin, beta-2
NPHS6	PTPRO	AR	614196	Protein-tyrosine phosphatase, receptor-type, O
NPHS7	DGKE	AR	615008	Diacylglycerol kinase, epsilon, 64-kDa
NPHS8	ARHGDIA	AR	615244	Rho GDP-dissociation inhibitor alpha
NPHS9	COQ8B	AR	615573	Coenzyme Q8B
NPHS10	EMP2	AR	615861	Epithelial membrane protein 2
NPHS11	NUP107	AR	616730	Nucleoporin, 107-kDa
NPHS12	NUP93	AR	616892	Nucleoporin, 93-kDa
NPHS13	NUP205	AR	616893	Nucleoporin, 205-kDa
NPHS14	SGPL1	AR	617575	Sphingosine-1-phosphate lyase 1
NPHS15	MAGI2	AR	617609	Membrane-associated guanylate kinase, WW and PDZ domain-containing, 2
NPHS16	KANK2	AR	617783	KN motif- and Ankyrin repeat domain-containing protein 2
NPHS17	NUP85	AR	618176	Nucleoporin, 85-kDa
NPHS18	NUP133	AR	618177	Nucleoporin, 133-kDa
NPHS19	NUP160	AR	618178	Nucleoporin, 160-kDa
NPHS20	TBC1D8B	XL	301028	TBC1 domain family, member 8B
NPHS21	AVIL	AR	618594	Advillin
FSGS1	ACTN4	AD	603278	Actinin, alpha 4
FSGS2	TRPC6	AD	603965	Transient receptor potential cation channel, subfamily C, member 6
FSGS3	CD2AP	AR/AD	607832	CD2-associated protein
FSGS4	APOL1	AR	612551	Apolipoprotein L-I
FSGS5	INF2	AD	613237	Inverted formin 2
FSGS6	MYO1E	AR	614131	Myosin IE
FSGS7	PAX2	AD	616002	Paired box protein 2
FSGS8	ANLN	AD	616032	Actin binding protein anillin
FSGS9	CRB2	AR	616220	Crumbs cell polarity complex component 2

AD, autosomal dominant; AR, autosomal recessive.

^aPhenotype number.