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. 2020 Mar 24;10:354. doi: 10.3389/fonc.2020.00354

Table 3.

PEWS-like-score (PEWS-LS) and critical deterioration in hospitalized pediatric hematology-oncology patients.

All events Critical deterioration Not critical deterioration p-value
n = 184 n = 92 n = 92
Hours of available data prior in 48 h prior to event, median (IQR) 46.5 (28.0, 47.6) 46.3 (25.6, 47.5) 46.8 (31.0, 47.8) 0.235a
PEWS-LS at time of PICU transfer, median (IQR) 4 (2, 4) 4 (3, 5) 3 (1, 4) <0.001a
Max PEWS-LS in 48 h prior to PICU transfer, median (IQR) 5 (4, 6) 5.5 (4, 6) 4 (4, 6) 0.001a
Percent of available time intervals in 48 h prior to PICU transfer with PEWS-LS ≥, median (IQR)
    PEWS-LS ≥3 34.6% (9.8%, 72.4%) 47.4% (14.0%, 76.7%) 27.2% (7.9%, 65.0%) 0.023a
    PEWS-LS ≥4 10.9% (1.8%, 35.1%) 15.2% (3.2%, 39.8%) 8.9% (0.5%, 31.2%) 0.045a
    PEWS-LS ≥5 1.5% (0%, 11.1%) 3.0% (0%, 13.7%) 0% (0%, 9.5%) 0.008a
Events with ≥6 h vital sign data Critical deterioration Not critical deterioration p-value
n = 174 n = 84 n = 90
Time (minutes) in 12 h prior to PICU transfer from first abnormal PEWS-LS, median (IQR)*
    PEWS-LS ≥3 615.0 (225.0, 720.0) 652.5 (367.5, 720.0) 562.5 (150.0, 720.0) 0.043a
    PEWS-LS ≥4 540.0 (0.0, 720.0) 622.5 (90.0, 720.0) 405.0 (0.0, 720.0) 0.028a
    PEWS-LS ≥5 60.0 (0.0, 720.0) 397.5 (0.0, 720.0) 0.0 (0.0, 705.0) 0.007a
*

Only events with at least 6 h of vital sign data prior to event start were included in this analysis (10 events excluded due to lack of adequate vital sign data).

a

Wilcoxon.

IQR, Inter-Quartile Range; PEWS-LS, Pediatric Early Warning System-Like-Score.