Table 1.

Semi-quantitative analysis of immunostaining for IL-1β, IL-6 and TNF-α in spleen of mice treated with AuNPs.

Groups	IL-1β		IL-6		TNF-α
	Day 1	Day 7	Day 1	Day 7	Day 1	Day 7
Control	0.75 ± 0.25		0.25 ± 0.25		0.00 ± 0.00
AuNP-5 nm	1.50 ± 0.28	2.25 ± 0.25*	1.25 ± 0.25	2.75 ± 0.25*	0.00 ± 0.00	0.25 ± 0.25
AuNP-20 nm	3.75 ± 0.25**	2.50 ± 0.28*	2.75 ± 0.25*	2.25 ± 0.25*	0.00 ± 0.00	0.00 ± 0.00
AuNP-50 nm	3.50 ± 0.28**	4.50 ± 0.28**	3.50 ± 0.28**	2.25 ± 0.25*	0.00 ± 0.00	0.00 ± 0.00

*P<0.05 and **P<0.01 versus control group using Dunnett’s test.