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. 2020 Mar 24;11:245. doi: 10.3389/fphar.2020.00245

Table 1.

Schedule and procedure of stressors used during 28 days of CUMS.

Day Stressor Duration
Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday
Physical restraint
Overnight illumination
Placement in an empty cage
Cold swim at 4°C
Tail pinch
Shaker stress
Food deprivation
Water deprivation
Cage tilt (45°)
Overnight illumination
Wet cages
Placement in an empty cage
Food deprivation
Water deprivation
2 h
12 h
24 h
5 min
1 min
5 min
24 h
24 h
24 h
12 h
24 h
24 h
24 h
24 h