TABLE 1.
FLS channel gene RNA expression lower after cytokine (10 ng/ml TNFα and IL1β) treatment.
| Gene | Official name | Log2 (95% CI) |
| Kcnj15 | Potassium inward rectified channel subfamily j member 15 | −5.51 (−9.57 to −2.48) |
| Ano2 | Anoctamin 2 | −2.59 (−5.5 to 0) |
| Kcnb1 | Potassium voltage-gated channel subfamily b member 1 | −2.44 (−1.85 to −1) |
| Kcnv2 | Potassium voltage-gated channel modifier subfamily v member 2 | −2.4 (−4.85 to 0) |
| Kcnip1 | Potassium voltage-gated channel interacting protein 1 | −2.36 (−3.88 to −0.88) |
| Kcnmb1 | Potassium calcium-activated channel subfamily m regulatory beta subunit 1 | −1.98 (−3.28 to 0.69) |
| Kcns1 | Potassium voltage-gated channel modifier subfamily s member 1 | −1.88 (−6.84 to −0.42) |
| Kcnj8 | Potassium inward rectifier j member 8 (Kir6.1) | −1.79 (−4.71 to 2.17) |
| Kcnd3 | Potassium voltage-gated channel subfamily d member 3 | −1.78 (−2.63 to 0.29) |
| Nalcn | Sodium leak channel, non-selective | −1.77 (−3.43 to −0.85) |
| Clca2 | Chloride channel accessory 2 | −1.76 (−6.72 to 0.65) |
| Kcne3 | Potassium voltage-gated channel subfamily e regulatory subunit 3 | −1.67 (−1.84 to −0.15) |
| Asic1 | Acid sensing ion channel subunit 1 | −1.64 (−6.44 to 0) |
| Clcn4 | Chloride voltage-gated channel 4 | −1.61 (−2.61 to −0.95) |
| Trpm8 | Trpm8 channel associated factor 1 | −1.61 (−2.09 to −0.99) |
Qualification cytokine log2 (geometric mean) < −1.5 of control (= approximately 33%), n = 4 control and 4 cytokine treated samples (from four animals).