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. 2020 Mar 24;11:226. doi: 10.3389/fphys.2020.00226

TABLE 2.

FLS channel gene RNA expression increased after cytokine (10 ng/ml TNFα and IL1β) treatment.

Gene ID Official name Log2 (95% CI)
Kcnc1 Potassium voltage-gated channel subfamily c member 1 4.32 (0.68 to 5.93)
Kcnc3 Potassium voltage-gated channel subfamily c member 3 3.46 (0.76 to 5.94)
Trpc3 Transient receptor potential cation channel subfamily c member 3 3.06 (3.73 to 6.5)
Catsper3 Cation channel sperm associated 3 2.83 (0.14 to 5.75)
Kcng3 Potassium voltage-gated channel modifier subfamily g member 3 2.81 (2.77 to 6.65)
Tmc7 Transmembrane channel like 7 2.77 (1.99 to 5.53)
Gjc3 Gap junction protein gamma 3 2.75 (0.03 to 4.35)
Scnn1g Sodium channel epithelial 1 gamma subunit 2.56 (2.77 to 5.45)
Asic2 Acid sensing ion channel subunit 2 2.52 (0.66 to 4.65)
Kcnmb3 Potassium calcium-activated channel subfamily m regulatory beta subunit 3 2.34 (0 to 4.73)
Cracr2a Calcium release activated channel regulator 2a 2.32 (0.01 to 1.96)
Kcnn3 Potassium calcium-activated channel subfamily n member 3 2.07 (0.57 to 4.09)
Tmc4 Transmembrane channel like 4 1.94 (0.27 to 2.47)
Asic4 Acid sensing ion channel subunit family member 4 1.75 (0.52 to 2.76)
Kcnj11 Potassium inward rectifier j member 11 (Kir6.2) 1.74 (0 to 6.56)
Trpv6 Transient receptor potential cation channel subfamily v member 6 1.7 (0.01 to 5.43)
Hvcn1 Hydrogen voltage gated channel 1 1.69 (0.98 to 2.84)
Trpv1 Transient receptor potential cation channel subfamily v member 1 1.61 (0.98 to 2.07)
Kcnk7 Potassium two pore domain channel subfamily k member 7 1.6 (−1.85 to 1.03)
Cacna1d Calcium voltage-gated channel subunit alpha1 d 1.57 (0.32 to 2.09)
Asic5 Acid sensing ion channel subunit family member 5 1.55 (0 to 5.78)

Qualification cytokine log2 (geometric mean) > 1.5 of control (= approximately 300%), n = 4 control and 4 cytokine treated samples (from four animals).