Figure 1. Severe acute respiratory syndrome-associated coronavirus virion.

Known structural surface proteins including the viral attachment protein S, small E and M protein are shown in black text, as well as potential (gray text) predicted membrane proteins that may or may not be in the virion. Predicted orientations of the protein are also shown relative to their N, as well as the topology regarding the size of the protein mass relative to the membrane of the virus particle [1]. Nomenclature is shown as in Genbank, except for ORF14, which is designated as in the original severe acute respiratory syndrome (SARS) genome sequence manuscript [1]. For proteins that are primarily external, the number of predicted amino acids displayed on the surface of the virion is shown. Y indicates that antibodies to thiS protein have been detected in SARS patient sera [35].

E: Envelope; M: Membrane/matrix; N: Amino terminal; S: Spike.