Hewett 2010.

Methods	Generation of allocation sequence: computer generated. Allocation concealment: Not applicable as not blinded Blinding: Not stated but not blinded to endoscopist Inclusion of all randomised patients: Yes
Participants	Number: 100 (57M:43F) Age: group 1: mean age 61.0 years +/‐ 1.0. Group 2: 62.9 +/‐1.2. Source:Indiana University Hospital, USA. Inclusion criteria: Patients 50 years of age or older and able to give informed consent, scheduled for elective colonoscopy. Exclusion criteria: ASA III or more, previous surgical resection of colon or rectum, IBD, current anticoagulant use.
Interventions	Colonoscope: High‐definition videocolonoscopes CF‐H180AL (Olympus, America). Bowel preparation: not stated. Intra‐procedure medication: propofol sedation "endoscopist‐directed". Endoscopist: "experienced". Caps: Soft, transparent plastic cap 13.4mm outer diameter, 4mm protrusion. (D‐201‐12704, Olympus).
Outcomes	Included in review: Caecal intubation time, Polyp detection rate Excluded from review: propofol dose, missed adenomas
Notes	Location: USA Source of funding: Not stated Attempts to clarify information: Not required Language of Publication: English
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer generated
Allocation concealment (selection bias)	High risk	Not blinded
Blinding (performance bias and detection bias) All outcomes	High risk	Not blinded to endoscopist.
Incomplete outcome data (attrition bias) All outcomes	Low risk	All data used for analysis
Selective reporting (reporting bias)	Low risk	Appropriate outcomes measured
Other bias	Unclear risk	Source of funding not stated.