Leborgne 1995.

Methods	RCT 1995‐2004
Participants	340 patients Stage IB2 to IVB
Interventions	Radiotherapy versus concomitant chemoradiotherapy (Cisplatin, 5‐FU)
Outcomes	Survival, disease‐free survival, local and distant recurrence
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Data checks on IPD provided suggest adequate sequence generation
Allocation concealment (selection bias)	Low risk	Sealed envelope
Blinding (performance bias and detection bias) All outcomes	High risk	Trial was not blinded due to nature of treatment interventions
Incomplete outcome data (attrition bias) All outcomes	Low risk	IPD provided for all outcomes except acute toxicity and late toxicity
Selective reporting (reporting bias)	Low risk	N/A (IPD supplied for all outcomes except acute toxicity and late toxicity)
Other bias	Low risk	Data checks on IPD provided suggest study is free of follow‐up bias