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. 2010 Jan 20;2010(1):CD008285. doi: 10.1002/14651858.CD008285

Peters 2000.

Methods RCT
1991 to 1996
Participants 268 patients
Stage IA2 to IIA
Interventions Surgery plus radiotherapy versus surgery plus concomitant chemoradiotherapy plus additional chemotherapy
Outcomes Survival, disease‐free survival, local and distant recurrence, acute toxicity
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Data checks on IPD provided suggest adequate sequence generation
Allocation concealment (selection bias) Low risk 'Assignment given by telephone upon study registration'
Blinding (performance bias and detection bias) 
 All outcomes High risk Trial was not blinded due to nature of treatment interventions
Incomplete outcome data (attrition bias) 
 All outcomes Low risk IPD provided for all outcomes except late toxicity
Selective reporting (reporting bias) Low risk N/A (IPD supplied for all outcomes except late toxicity)
Other bias Low risk Data checks on IPD provided suggest study is free of follow‐up bias