Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Current view of the renin–angiotensin system. Angiotensin I serves as a substrate for both ACE and ACE2. Angiotensin II is known to act as vasoconstrictor as well as mitogen for smooth muscle cells or fibroblasts, mainly through the angiotensin II type 1 receptor. The function of angiotensin 1–9 is not well understood. Both ACE and ACE2 are involved in the production of the vasodilator peptide angiotensin 1–7.
