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. 2006 Nov 9;3(3):247–253. doi: 10.1016/j.ddtec.2006.09.008

Table 1.

Comparison summary table

Technology 1 Technology 2 Technology 3
Name of specific type of technology
CADDa based on TCMb
FAC–MSc for screening
MIP-SPEd for screening and separating
Names of specific technologies with associated companies and company Web sites Accelrys, Inc. http://www.accelrys.com/ Applied Biosystems http://www.appliedbiosystems.com/ Applied Biosystems http://www.appliedbiosystems.com/

Neotrident Technique Ltd. http://www.neotrident.com/


Pros Virtual screening based on TCM database has higher hit rate than that based on chemical database Only for screening, higher hit rate Combining the screening, separating and identifying on one single step


No false leads

Cons
High throughput
Relatively high throughput
Relatively high throughput
References [9, 10] [19, 20, 23] [27, 29]
a

Computer-aided drug design.

b

Traditional Chinese medicine.

c

Frontal affinity chromatography with mass spectrometry.

d

Molecularly imprinted polymers in solid phase extraction.