Table 1.

Rabbit models of heart disease

Experimental conditions	Refs
(a) Volume overload
Arterio-venous shunt formation	[8]
Aortic regurgitation	[9, 10]
(b) Models of ventricular hypertrophy
Chronic AV block	[12]
Chronic infusion of angiotensin	[18]
LV pressure overload
Aortic constriction	[13, 14, 15]
Nephrectomy (hypertension)	[16, 17]
RV pressure overload
Pulmonary artery constriction – adult	[19]
Pulmonary artery constriction – young	[20]
Monocrotaline-induced pulmonary hypertension	[21]
(c) Ischemic heart disease models
Myocardial infarction in the rabbit
Coronary artery occlusion	[23, 24]
Myocardial ischemia followed by reperfusion	[27]
Intracoronary microsphere embolization	[28]
Direct current shock	[30]
Hibernating myocardium
Coronary artery ligation	[31]
Cellular model	[32]
(d) Heart failure
Adriamycin cardiomyopathy	[37, 38, 39]
High-dose catecholamines	[42]
Pacing-induced heart failure	[44, 45, 46, 47]
Combined pressure and volume overload	[5, 52, 54, 59, 61]
(e)In vivoarrhythmia models
Torsades des pointes	[62, 63, 64, 65]
Atrial fibrillation
Isolated rabbit atria prep	[67, 68, 69]
Ventricular tachypacing-induced HF	[71]
(f) Transgenic rabbit models of heart disease
Long QT syndrome	[72]
Hypertrophic cardiomyopathy	[73, 74]
Gsα overexpression	[75]
Phospholamban overexpression	[76]
(g) Other rabbit cardiac models
Myocarditis
Viral (coronavirus and coxsackie virus)	[77, 78]
Fungal (Cryptococcus)	[79]
Parasitic (toxoplasmosis)	[80]
Bacterial (streptococci and diphtheria)	[81, 82]
Chronic Chagas disease (Trypanosoma cruzi)	[83, 84]
Bacterial endocarditis (streptococcus, enterococcus and staphylococcus)	[85]
Radiation-induced heart disease	[87]