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. 2019 Jan 3;68:58–67. doi: 10.1016/j.intimp.2018.09.043

Table 1.

IC50 values of ARB on Vero cells as determined by the CPE method and MTT assay.

Drugs TC50 (μg/m) HSV-2 (CPE assay)
HSV-2 (MTT assay)
IC50 (μg/mL) SIa IC50 (μg/mL) SIa
ARB 32.605 ± 0.02 5.045 ± 0.33 6.46 4.77 ± 0.29 6.82
ACV 195.64 ± 11.37 38.30 ± 6.67 5.11 33.135 ± 7.01 5.91

IC50 (μg/mL) values and TC50 (μg/mL) values were predicted according to the best fitting nonlinear regression formula calculated for each set of data.

a

“SI” is the abbreviation of “the selection index”. SI > 2 means low toxicity; 2 > SI > 1 means high toxic and low effect; SI ≤ 1 means no effect.