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Effect of ARB treatment on the protection of mice infected intravaginally with HSV-2.
| Group | Survivors/total | Protection index | Average survival time (d) |
|---|---|---|---|
| ARB ointment (100 mg/kg/d) | 8/10⁎⁎⁎ | 71.4% | 14.1 ± 1.91 |
| ARB (100 mg/kg/d) | 3/10 | 0% | 11.8 ± 2.49 |
| ACV (100 mg/kg/d) | 8/10⁎⁎⁎ | 71.4% | 14.3 ± 1.64 |
| Virus group | 3/10# | – | 12.0 ± 2.62 |
| Normal group | 10/10 | 100% | >15.0 |
Note: Drug group compared with virus group: ⁎⁎⁎p < 0.001. Virus group compared with normal group: #p < 0.05.
