Fig. 2.
Immunostimulation of equine F(ab′)2 to macaque immune organs. The macaques received successive injections of 5 mg/kg body weight of equine anti-SARS–CoV F(ab′)2 everyday for 4 weeks with or without a 3-week recovery after the last injection. Panel A, the spleen of monkey injected with saline. Panels B and C, the spleen from a successively injected monkey. Panel D, the spleen from a monkey received successive injections but with a 3-week recovery after the last injection. Panel E, the lymph node of monkey injected with saline. Panels F and G, the lymph node from a successively injected animal. Panel H, the lymph node from a monkey that received successive injections with a 3-week recovery after the last injection. Panel I, the injection site of a saline-injected control macaque. Panel J, the injection site of a macaque that received successive injections. Panel K, the injection site of an animal injected successively but with a 3-week recovery after the last injection. The staining method and the magnification for each photo were indicated.