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Overall number of TCC generated throughout this study
| Donors | n1 | Monospecific |
n2 | Cross-reactive |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Viral Ag |
Myelin Ag |
Viral Ag |
Myelin Ag |
|||||||
| 229E | OC43 | MBP | PLP | 229E | OC43 | MBP | PLP | |||
| 80 | 34 | 19 | 12 | 4 | 2 | 2 | 2 | |||
| MS | 32 | 114 | 31 | 6 | 6 | 4 | ||||
From the blood of 32 donors (n1), we generated 145 long-term primary TCC selected with either viral or myelin Ag and 10 HCoV-myelin cross-reactive TCC were produced from the blood of 6 out of these 32 MS patients (n2).
