Table 3.
Parameter estimates, dN/dS, values of log-Likelihood (l), positive selection sites, and Likelihood Ratio Tests (LRT) in the G gene analysis of HRSV-A isolated in South Korea between 2008 and 2013.
| Model | Parameter estimates | dN/dS | Log-likelyhood (l) | Positively selected sites⁎ | Model comparison |
|---|---|---|---|---|---|
| M1 | w0 = 0.0 | 0.6688 | −818.392077 | 8.71 | |
| w1 = 1.0 | d.f. = 2, p < 0.05 | ||||
| p0 = 0.33115 | |||||
| p1 = 0.66885 | |||||
| M2† | w0 = 0.15815 | 1.1852 | −814.034775 | V225A, E232G/D, D237N/Y, L247M, S250N, N251Y/S, T253K/I, P256L, E262R, L274P/T, Y280H, E309T, L311H/P, S312N, Q313L, S314Y/P, S316H, S317P, N319Q, T320Q/I, T321N/S, K322D | |
| w1 = 1.0 | |||||
| w2 = 2.31504 | |||||
| p0 = 0.52384 | |||||
| p1 = 0.0 | |||||
| p2 = 0.47616 | |||||
| M7 | p = 0.01165 | 0.70 | −817.440963 | 6.81 | |
| q = 0.00500 | d.f. = 2, p < 0.05 | ||||
| M8‡ | p0 = 0.52384 | 1.1849 | −814.035088 | V225A, E232G/D, D237N/Y, L247M, S250N, N251Y/S, T253K/I, P256L, N260S, E262R, N273Y, L274P/T, Y280H, E309T, L311H/P, S312N, Q313L, S314Y/P, S316H, S317P, N319Q, T320Q/I, T321N/S, K322D | |
| p1 = 0.47616 | |||||
| p = 18.69927 | |||||
| q = 99.0 | |||||
| w = 2.31393 | |||||
HRSV, human respiratory syncytial virus.
Sites were numbered as based on ON1 sequence (ON67-1210A, Genbank accession No. JN257693).
Posterior probability of positively selected sites with M2 model: 50% to 74% (232, 317, 225, 253, 280, 319, 256, 250, 313, 251, 247, 321, 312); 75% to 84% (316, 314, 262, 311, 320); 85% to 94% (322, 309, 274, 237); and 95% < (none).
Posterior probability of positively selected sites with M8 model: 50% to 74% (260, 273, 232, 280, 317, 225, 253, 319, 256, 247, 250, 313, 251); 75% to 84% (none); 85% to 94% (321, 312, 316, 314, 262, 311, 320, 309); and 95% < (322, 274, 237).