Fig. 6.
Effects of Si-Ni-San, glycyrrhizin, and the glycyrrhizin-depleted sample of Si-Ni-San (Si-Ni-SanGL−) on the productions of MMP-2 and MMP-9 in splenocytes isolated from PCl-sensitized mice. A and B: MMP-2. C and D: MMP-9. Five days after PCl sensitization, the isolated spleen cells were incubated with Si-Ni-San, glycyrrhizin and Si-Ni-SanGL− all at 10− 4 g/mL at 37 °C for 24 h. After the incubation, the supernatants were aspirated and used for zymography assay. The figure shown here is the representative of three different experiments.