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. 2014 May 7;11(8):e9–e51. doi: 10.1016/j.hrthm.2014.03.042

Table 3.

Procedural Complications

Complication Prevention Diagnosis Treatment
EP catheter procedural complications
Pericardial effusion/tamponade Avoid excess catheter force Fluoroscopy of cardiac border,63 2D echocardiography Reversal of anticoagulation, urgent pericardiocentesis
AV nodal block Monitor for accelerated junctional rhythm, VA block, AV block during overdrive atrial pacing ECG Pacemaker
Phrenic nerve palsy Phrenic nerve mapping, phrenic nerve pacing during RSPV, SVC, and LAA ablation64, 65, 66 Fluoroscopy, chest radiography Conservative therapy
Stroke Anticoagulation (ACT >300 or 350 s in the LA), avoid char formation Neurological exam, MRI scan (DWI and FLAIR imaging) Conservative therapy, Merci thrombectomy
Coronary artery injury Avoid excess power delivery in the CS, coronary angiography before epicardial ablation, coronary ostia visualization by angiography and ICE before ablation in the aortic root ECG Percutaneous intervention
Access site complications (hematoma, AV fistula, pseudoaneurysm) Site selection, excellent technique, vascular ultrasound to guide puncture,67 micropuncture Physical exam, ultrasound Manual pressure, bed rest
Radiation burn Minimize radiation exposure Physical exam (presentation typically 2–8 wk postprocedure, but can be >40 wk) Avoid repeat exposure
CIED implant procedural complications
Pneumothorax Extrathoracic vascular access (axillary or cephalic vein) Chest radiography 100% oxygen rebreather, chest tube
Lead dislodgement Test lead for acute fixation (“tug test”) ECG, device interrogation, chest radiography Reoperation and repositioning
Pericardial effusion/tamponade Avoid excess forward pressure during lead placement Fluoroscopy of the cardiac border,63 2D echocardiography Urgent pericardiocentesis
Pocket hematoma Avoid heparin and clopidogrel Exam Conservative therapy, pressure wrap, reoperation for pocket evacuation
Infection Preoperative antibiotics, prevent hematoma,67 score or excise chronic pocket fibrosis Exam, wound culture, blood culture Antibiotics, extraction of the entire system (unless superficial)
Air embolism Use introducer sheaths with hemostatic valves Fluoroscopy 100% oxygen rebreather
Postprocedural complications
Hematoma Avoid heparin and clopidogrel Exam Conservative therapy
Infection Good wound care Exam, wound culture, blood culture Antibiotics, extraction of entire system (unless superficial)
Late pericardial effusion/tamponade None 2D echocardiography Pericardiocentesis
Phrenic nerve palsy Phrenic nerve mapping, phrenic nerve pacing during RSPV, SVC, and LAA ablation64, 65, 66 Loss of diaphragmatic motion on fluoroscopy, elevated hemidiaphragm Conservative therapy
Stroke Postprocedure anticoagulation68 Neurological exam, MRI scan (DWI and FLAIR imaging) Conservative therapy, consider Merci thrombectomy
Myocardial infarction Appropriate anticoagulation ECG, biomarkers Medical therapy, percutaneous intervention
Atrial-esophageal fistula Limit power, time, temperature, pressure during posterior wall ablation, monitor esophageal temperature Fever, malaise, leukocytosis, systemic embolism, CT or MRI findings Surgery
New arrhythmias Avoid creation of gaps in linear ablation ECG, ambulatory monitor Antiarrhythmic drugs, repeat catheter ablation
Radiation burn Minimize radiation exposure Physical exam (presentation typically 2–8 wk postprocedure, but can be >40 wk) Avoid repeat exposure

2D = two-dimensional; ACT = activated clotting time; AV = atrioventricular; CS = coronary sinus; CT = computed tomography; DWI = diffusion weighted imaging; ECG = electrocardiogram; EP = electrophysiology; FLAIR = fluid-attenuated inversion recovery; ICE = intracardiac echocardiography; LA = left atrium; LAA = left atrial appendage; MRI = magnetic resonance imaging; RSPV = right superior pulmonary vein; SVC = superior vena cava; VA = ventricular atrial.