Table 1.
Conserved sequences from the nucleocapsid (N) and glycoprotein (G) of RVFV.
| Conserved sequences | Position | VaxiJen score | Transmembrane helix |
|---|---|---|---|
| Nucleocapsid (N) | |||
| MDNYQELAIQFAAQAVDRNEIEQWVREFAYQGFDARRVI ELLKQYGGADWEKDAKKMIVLALTRGNKPRRMMMKMS KEGKATVEALINKYKLKEGNPSRDELTLSRVAAALAG |
1–113 | 0.3589 | Outside |
| TCQALVVLSEWLPVTGTTMDGLS | 115–137 | 0.4542 | Outside |
| PRHMMHPSFAGMVDPSLP | 141–158 | 0.7857 | Outside |
| DYLRAILDAHSLYLLQFSRVINPNLRGRTKEEVAATFTQP MNAAVNSNFISHEKRR |
160–215 | 0.5662 | Outside |
| FLKAFGLVDSNGKPSAAV | 217–234 | 0.5546 | Outside |
| Glycoprotein (G) | |||
| EAVIRVSLSSTREETCFGDSTNPEMIE | 15–41 | 0.8871 | Outside |
| AWDSLREEEMPEELSCSISGIREVKTSSQELYRALKAIIAAD GLNNITCHGKDPEDKISLIKGPPHKKRVGIVRC |
42–117 | 0.2465 | Outside |
| RETMAGIAMTVLPALAVFALAPVVFAED | 128–155 | 0.6132 | Outside, TMhelix inside |
| HLRNRPGKGHNYIDG | 157–171 | − 0.0385 | inside |
| QEDATCKPVTYAGACSSFDVLLEKGKFPLFQSYAHHRTLL EAVHDTIIAKADPPSCDL |
174–234 | 0.3368 | inside |
| CMKEKLVMKTHCPNDYQSAHYLNNDGKMASVKCPPKYE LTEDCNFCR |
239–285 | 0.3555 | inside |
| MTGASLKKGSYPLQDLFCQSSEDDGSKLKTKMKGVCEVG VQALKKCDGQLSTAHEVVPFAVFKNSKKVYLDKLDLKTE ENLLPDSFVCFEHKGQYKGTM |
287–385 | 0.5831 | Outside |
| SGQTKRELKSFDISQCPKIGGHG | 387–409 | 0.8886 | inside |
| TGDAAFCSAYECTAQYANAYCSHANGSGIVQIQVS | 414–448 | 0.2323 | Outside |
| VWKKPLCVGYERVVVKRELSAKPIQRVEPCTTCITKCEPH GLVVRSTGFKISSAVACASGVCVTGSQSPSTEITLKYPGISQSS |
450–533 | 0.5311 | Outside |
| GDIGVHMAHDDQSVSSKIV | 535–553 | 0.6649 | Outside |
| HTALSAFVVVFVFSS | 580–594 | 0.1602 | Outside |
| AIICLAILYKVLKCLKIAPRKVLNPLMWITAFIRWVYKKM VARVADNINQVNREIGWMEGGQL |
596–658 | 0.5367 | Outside |
| NPAPIPRHAPIPRYSTYLMLLLIVSYASACSELIQASSRITTC STEGVNTRCRLS |
662–716 | 0.3969 | Outside, TMhelix inside |
| DQTKFLKIKTVSSELSCREGQSYWTGSFSPKCLSSRRCHLV GECHVNRCLSWRDNETSAEFSFVGESTTMRENKCFEQCG GWGCGCFNVNPSCLFVHTYLQS VRKEALRVFNCIDWVHKLTLEITDFDGSVSTIDLGASSSRF TNWGSVSLSLDAEGISGSNSFSFIESPGKGYAIVDEPFSEIP RQGFLGEIRCNSESSVLSAHESCLRAPNLISYKPMIDQLECT TNLIDPFVVFERGSLPQTRNDKTFAASKGNRGVQAFSKGS VQADLTL |
740–1013 | 0.6272 | Outside |
| FDNFEVDFVGAAVSCDAAFLNLTGCYSCNAGARVCLSITS TGTGTLSAHNKDGSLHIVLPSENGTKDQCQILHFTVPEVEE EFMYSCDGDERPLLVKGTLIAIDPFDDRREAGGESTVVNP KSGSWNFFDWFSGLMSWFGGPLKTILLICLYVALSIGLFFL LIYLGRTGLSKMWLAATKKAS |
1015–1197 | 0.5974 | Outside, TMhelix inside |