Table 2.
Summary of studies prospectively following infants post bronchiolitis. PFT, pulmonary function test
| Author | Year published | Bont et al. Review28 | Semple and Smyth review29 | Perez Yarza et al. review30 | Hospital admissions | Controls | Follow-up years | Outcome |
Associated with parental atopy | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Wheeze | Asthma | Lung function | |||||||||
| Eisen | 1963 | Y | Y | N | Y | N | 14 | Y 49% | N | ||
| Sims | 1978/1981 | Y/Y | Y | N | Y | Y | 8 | 56% | Reduced | N | |
| Mok | 1982 | Y | Y | N | Y | Y | 7 | Y | Reduced | N | |
| Korppi | 2004 | Y | Y | Y | Y | non-atopic | 20 | No difference | Reduced | N/A | |
| Gurwitz | 1981 | Y | Y | N | Y | N | 8 | 52% | Reduced | N/A | |
| Pulan | 1982 | Y | Y | N | Y | Y | 10 | 42% | Reduced | N | |
| Bont | 2000 | Y | Y | N | N | Y | 8 | 44% | N | ||
| Hall | 1984 | Y | Y | N | Y | Y | 8 | 45% | Reduced | N | |
| Welliver | 1993 | Y | Y | N | Y | N | 2 | 53% | Nasal IgE predicts | N/A | |
| Sly | 1989 | Y | Y | N | Y | N | 5 | 71% | N | ||
| Murray | 1992/1997 | Y/Y | Y | N | Y | N | 5 and 10 | 43% | Reduced | N | |
| Osundwa | 1993 | Y | Y | Y | Y | Y | 2 | 44% | N | ||
| Sigurs | 1995/2000/2005 | Y/Y/N | Y | Y/Y/Y | Y | Y | 3, 7, 13 | 60%, 30%, 43% | Y | ||
| Renzi | 1997 | N | Y | N | Y | N | 3 months | 65% | Th2 cytokines | N/A | |
| Bont | 2004 | N | Y | N | Y | N | 3 | Wheeze if reduced PFT | N | ||
| Stein | 1999 | N | Y | Y | N | Y | 13 | Up to 11 but not 13 years | N | ||
| Bont | 2000/2004 | Y/N | Y | N | Y | Y | 1 and 3 | IL-10 associated | N | ||
| Schauer | 2002 | Y | Y | Y | Y | Y | 1 | Y | N | ||
| Fjaerli | 2005 | N | N | Y | Y | Y | 7 | 48% | 60% | N/A | |
| Henderson | 2005 | N | N | Y | Y | Y | 7 | Y OR 2.3 | Y OR 2.5 | N/A | |
| Singleton | 2003 | N | N | Y | Y | N | 5 | N | Y RR 3.1 | N/A | |
| Weber | 1999 | N | N | Y | Y | N | 3 | Y | N/A | ||
| Juntti | 2003 | N | N | Y | N | Y | 5–10 | Y OR 0.9 | Y OR 13.4 | N | N |