TABLE 2.
| Pathogen | Animal model | Insert | Immune response | References |
|---|---|---|---|---|
| Human immunodeficiency virus/simian immunodeficiency virus | Rodent, NHP, human | Gag, Pol, Nef, Env | CMI and antibody | [31], [73], [89], [90], [107], [108], [109] |
| Rabies virus | Rodent, dog | Glycoprotein | CMI and antibody | [40], [68], [70], [71], [93], [94], [110], [111], [112] |
| Dengue virus | Rodent | Envelope | CMI and antibody | [113] |
| Ebola virus | Rodent, NHP | Glycoprotein, nucleoprotein | CMI and antibody | [83], [114] |
| SARS–coronavirus | Rodent, NHP | Spike, nucleocapsid, membrane protein | CMI and antibody | [81] |
| Human papillomavirus | Rodent, NHP | L1, E5, E6, E7, | CMI and antibody | [41], [115], [116] |
| Hepatitis C virus | Rodent | E1, E2, core, NS3 | CMI and antibody | [42], [117], [118], [119], [120] |
| Hepatitis B virus | Rodent, dog, NHP | Surface antigen | Antibody | [121], [122] |
| Rotavirus | Rodent | VP7sc | Antibody | [123], [124] |
| Measles virus | Rodent | Nucleocapsid, hemagglutinin, fusion protein | CMI and antibody | [72], [125], [126], [127] |
| Respiratory syncytial virus | Rodent, dog, NHP | Glycoprotein | Antibody | [128], [129] |
| Cytomegalovirus | Rodent | Glycoprotein B | Antibody | [130], [131] |
| Herpes simplex 2 virus | Rodent | Glycoprotein B | CMI and antibody | [132], [133] |
| Epstein–Barr virus | Rodent | Latent membrane proteins 1 + 2, envelope glycoprotein | CMI and antibody | [134], [135] |
Abbreviations: CMI, cell-mediated immunity; NHP, nonhuman primate.