Fig. 2.

H & E stained PCLTS after 24 h mycobacterial infection. Panels A and B correspond to lung tissue from uninfected PCLTS. Alveolar septa, pneumocytes type I (asterisk) and pneumocytes type II (arrow heads) are evident (panel B). Panels C and D correspond to M. tuberculosis H37Rv-infected PCLTS, while panels E and F to M. bovis BCG-infected PCLTS. In mycobacteria-infected PCLTS, there is an increase of inflammatory response predominantly lymphocytic (circles) (panels D and F). Magnification: 100× (A, C, and E) or 400× (B, D, and F).