Table 2.
Comparison of Medication Administrations, Chest X-rays, Turn-around-Time, and LOS by MRP Assay Type.
| Unadjusted |
Adjusted b |
|||||
|---|---|---|---|---|---|---|
| Luminex | Biofire | p-value a | OR (95% CI) | p-value | ||
| Empiric antibiotics -- no. (%) | 646 (51.1%) | 1239 (32.0%) | <.001 | 0.45 (0.39, 0.52) | <.001 | |
| Empiric broad-spectrum | 447 (35.4%) | 829 (21.4%) | <.001 | 0.50 (0.43, 0.58) | <.001 | |
| Broad-spectrum duration (hours) c -- median [IQR] | 32.9 [22.9, 45.8] | 6.4 [1.9, 13.2] | <.001 | --- | --- | |
| Empiric narrow-spectrum -- no. (%) | 382 (30.2%) | 625 (16.1%) | <.001 | 0.44 (0.38, 0.52) | <.001 | |
| Narrow-spectrum duration (hours) c-- median [IQR] | 31.4 [18.1, 43.4] | 9.1 [6.1, 16.3] | <.001 | --- | --- | |
| Oseltamivir post-test d -- no. (%) | 23 (19.3%) | 124 (79.0%) | <.001 | 13.56 (7.29, 25.20) | <.001 | |
| Chest x-rays within 48 hours of admission | 803 (63.5%) | 2245 (57.9%) | <.001 | 0.71 (0.62, 0.82) | <.001 | |
| Length of stay (hours) -- median [IQR] | 54.3 [38.6, 89.0] | 49.0 [32.2, 78.9] | <.001 | --- | --- | |
| Turn-around-time (hours) | 27.1 [24.7, 50.3] | 1.4 [1.2, 1.7] | <.001 | --- | --- | |
Abbreviation: IQR, inter-quartile range; OR, odds ratio; CI, confidence interval.
a
Based on Fisher's Exact test for categorical and Kruskal-Wallis test for continuous.
b
Odds relative to Luminex after adjusting for patient age, organism, location, and calendar quarter.
c
Among patients with more than one empiric antibiotic administration.
d
Among patients positive for influenza.