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Cytokine and chemokine levels during the course of the disease. (A–C) The levels of IFN-α, IL-10, and IP-10 increased during the early course of disease and decreased subsequently. (D–J) The concentrations of TNF-α, IL-1β, IL-12p40, IL-13, IL-17A, RANTES, and VEGF in plasma tended to increase during the late course of disease.
