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. 2019 Apr 25;116:S28–S33. doi: 10.1016/j.tube.2019.04.008

Fig. 1.

Fig. 1

Niclosamide inhibits growth of M. bovis BCG and virulent M.tb Beijing in liquid culture. 5 mL static cultures of A)M. bovis BCG or B)M.tb Beijing were grown to O.D. 0.2, then grown in the presence of rifampicin, isoniazid, or increasing concentrations of niclosamide from 2.5 to 20 μM for 7 days. CFU were calculated from final O.D. readings using the estimate of 1 OD = 3 × 108/ml. Niclosamide limited mycobacterial growth in a dose-dependent manner. Data represent the average of three experiments, plus or minus SE. All treatments were significantly different than control with p < .05.