Table 2.
Multivariate analysis in 83 lung transplant recipients.
| Coefficient | 95% CI | p value | |
|---|---|---|---|
| CD4 T-cell counta | |||
| Viral infections in blood (yes vs. no)b | −11.1 | −50.0 to 27.9 | 0.578 |
| Gender (males vs. females) | 45.7 | −60.5 to 151.9 | 0.399 |
| Age (per year) | 1.3 | −2.3 to 4.9 | 0.494 |
| Nadir CD4 T-cell (< 200 vs. > 200 cells/μl) | −423.4 | −516.8 to −329.9 | <0.001 |
| Induction therapy (ATG vs. no) | −95.9 | −203.1 to 11.1 | 0.079 |
| Immunosuppressive therapyc | −45.1 | −138.7 to 48.6 | 0.345 |
| Rejection episodes (yes vs. no) | −20.2 | −65.3 to 24.9 | 0.380 |
| Viral infections in BAL (yes vs. no)b | −28.4 | −-54.8 to −1.9 | 0.036 |
| Gender (males vs. females) | 45.1 | −61.9 to 152.1 | 0.409 |
| Age (per year) | 1.3 | −2.3 to 4.9 | 0.473 |
| Nadir CD4 T-cell (< 200 vs. > 200 cells/μl) | −421.7 | −515.9 to −327.5 | <0.001 |
| Induction therapy (ATG vs. no) | −93.9 | −201.7 to 13.8 | 0.088 |
| Immunosuppressive therapyc | −43.1 | −137.3 to 51.1 | 0.370 |
| Rejection episodes (yes vs. no) | −10.6 | −56.3 to 35.1 | 0.649 |
| CD8 T-cell counta | |||
| Viral infections in blood (yes vs. no)b | −36.2 | −101.8 to 29.4 | 0.279 |
| Gender (males vs. females) | 206.8 | 44.1 to 369.6 | 0.013 |
| Age (per year) | −4.7 | −10.2 to 0.8 | 0.096 |
| Nadir CD4 T-cell (< 200 vs. > 200 cells/μl) | −300.6 | −443.1 to −158.1 | <0.001 |
| Induction therapy (ATG vs. no) | −58.9 | −223.3 to 105.3 | 0.482 |
| Immunosuppressive therapyc | 44.7 | −98.9 to 188.4 | 0.542 |
| Rejection episodes (yes vs. no) | 64.6 | −11.2 to 140.4 | 0.095 |
| Viral infections in BAL (yes vs. no)b | −12.1 | −56.9 to 32.7 | 0.596 |
| Gender (males vs. females) | 208.6 | 45.1 to 372.0 | 0.012 |
| Age (per year) | −4.7 | −10.2 to 0.9 | 0.098 |
| Nadir CD4 T-cell (< 200 vs. > 200 cells/μl) | −303.2 | −446.2 to −160.1 | <0.001 |
| Induction therapy (ATG vs. no) | −53.9 | −218.6 to 110.9 | 0.522 |
| Immunosuppressive therapyc | 39.9 | −103.9 to 183.8 | 0.587 |
| Rejection episodes (yes vs. no) | 69.9 | −7.2 to 147.2 | 0.076 |
CI, confidence interval; ATG, antithymocyte globulin; BAL, bronchoalveolar lavage.
Dependent variable.
Both opportunistic and community-acquired viral infections.
Cyclosporine A or tacrolimus/azathioprine/steroids vs. Cyclosporine A or tacrolimus/mycophenolate mofetil/steroids.