Table 3.
Comparison with other Brassica antifungal peptides.
| Campesin, (B. campestris (this study) | BCLTP (B. campestris) (29) | Antifungal peptide (B. alboglabra)(28) | Antifungal peptide (B. parachinensis) (27)a | |
|---|---|---|---|---|
| Molecular weight | 9.4 kDa | 9414 Da | 5907 Da | 5716 Da |
| Lipid transfer activity | Present | Present | Absent | Absent |
| Antifungal activity (IC50) | Mycosphaerella arachidicola: 4.4 μM | M. arachidicola: 8.3 μM | M. arachidicola: 2.4 μM | M. arachidicola: 2.6 μM |
| Fusarium oxysporum: 5.1 μM | F. oxysporum: 4.5 μM | F. oxysporum: 4.3 μM | F. oxysporum: 3.9 μM | |
| Antitumor activity (IC50) | HepG2: 6.4 μM | HepG2: 5.8 μM | HepG2: 2.7 μM | HepG2: 19.2 μM |
| MCF7: 1.8 μM | MCF7: 1.6 μM | MCF7: 3.4 μM | MCF7: 4.8 μM | |
| Antiproliferative activity on normal human embryonic liver cells (WRL68) | Devoid of activity | Not tested | Not tested | Not tested |
| Anti-HIV reverse transcriptase activity (IC50) | 3.2 μM | 4 μM | 4.9 μM | 17.8 μM |
| pH stability of antifungal activity | Stable from pH 0–14 | Stable from pH 0–14 | Stable from pH 2–11 | Stable from pH 1–13 |
| Thermostability | Up to 100 °C (shown for all aforementioned activities) | Up to 100 °C (shown for all aforementioned activities) | Up to 80 °C (shown for antifungal activity only) | Up to 100 °C (shown for antifungal activity only) |