Table 1.
General characteristics of study subjects by quartiles of serum angiotensin-converting enzyme 2 (ACE2) levels on postoperative day 1.
| Serum ACE2 levels (ng/mL) |
p | ||||
|---|---|---|---|---|---|
| ≤3.21 (n = 80) |
3.22-3.86 (n = 80) |
3.87-4.42 (n = 80) |
≥4.43 (n = 80) |
||
| Age (years) | 64.3±9.5 | 64.1 ± 8.8 | 63.6 ± 9.2 | 63.1 ± 10.2 | 0.33 |
| Age group (years) n(%) | |||||
| ≤50 | 8 (10.0) | 8 (10.0) | 7 (8.8) | 9 (11.3) | 0.98 |
| 51-60 | 15 (18.8) | 19 (23.8) | 21 (26.2) | 22 (27.5) | |
| 61-70 | 24 (30.0) | 21 (26.2) | 22 (27.5) | 20 (25.0) | |
| 71-80 | 33 (41.2) | 32 (40.0) | 30 (37.5) | 29 (36.2) | |
| Sex n(%) | |||||
| Male | 51 (63.8) | 49 (61.3) | 55 (68.8) | 50 (62.5) | 0.77 |
| Female | 29 (36.2) | 31 (38.7) | 25 (31.2) | 30 (37.5) | |
| Pulmonary resection n(%) | |||||
| Pneumonectomy | 10 (12.5) | 10 (12.5) | 7 (8.8) | 8 (10.0) | 0.80 |
| Lobectomy | 66 (82.5) | 64 (80.0) | 70 (87.5) | 65 (81.2) | |
| Bilobectomy | 4 (5.0) | 6 (7.5) | 3 (3.7) | 7 (8.8) | |
| FEV1 (%) | 77.5 ± 5.4 | 76.9 ± 5.9 | 76.4 ± 6.5 | 75.8 ± 6.9 | 0.20 |
| Coronary heart disease n(%) | 14 (17.5) | 11 (13.8) | 11 (13.8) | 10 (12.5) | 0.82 |
| Hypertension n(%) | 31 (38.8) | 28 (35.0) | 27 (33.8) | 23 (28.8) | 0.61 |
| Diabetes mellitus n(%) | 14 (17.5) | 13 (16.3) | 15 (18.8) | 11 (13.8) | 0.85 |
| COPD n(%) | 40 (50.0) | 35 (43.8) | 36 (45.0) | 31 (38.8) | 0.56 |
| Body mass index (kg/m2) | 17.5 ± 4.2 | 17.9 ± 5.0 | 18.3 ± 4.7 | 18.1 ± 2.9 | 0.35 |
| Current smoking | 32 (40.0) | 27 (33.8) | 36 (45.0) | 30 (37.5) | 0.52 |
Note: FEV1, forced expiratory volume in 1 second; COPD, chronic obstructive pulmonary disease.