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. 2020 Mar 30;12:50. doi: 10.1186/s13148-020-00841-5

Table 3.

Results from combined model and ANOVA comparing this with models for methylation and genetic scores

Combined model adjusted R-squared1 ANOVA (model 1 vs model 3) ANOVA (model 2 vs model 3)
Birth 0.03 0.04 1.56E−09
Childhood 0.04 9.03E−09 1.28E−03
Adolescence 0.08 1.93E−10 5.28E−11
Pregnancy 0.04 2.22E−04 5.36E−05
Middle age 0.12 2.77E−05 4.55E−21

1Adjusted R-squared obtained from model with both the methylation and the genetic scores and no other covariates

Model 1 includes the methylation score, model 2 includes the genetic score and model 3 is the combined model including the methylation and genetic score. All models also included the relevant covariates