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. 2020 Mar 30;20:123. doi: 10.1186/s12886-020-01395-z

Table 2.

Psychiatric disorder conditions as defined by ICD-9-CM in PD patients with and without dry eye for the period 1997–2011

Dry Eye Syndrome
No
n = 71,985
Yes
n = 3665
Psychiatric disorder condition (ICD-9-CM) n (%) n (%) p-value
Dementia (290, 331.0, 331.2) 7426 (10.3) 534 (14.6) < 0.001
Alcoholic psychoses (291) 1707 (2.4) 35 (1.0) < 0.001
Drug psychoses (292) 1339 (1.9) 38 (1.0) < 0.001
Schizophrenia (295) 4242 (5.9) 151 (4.1) < 0.001
Bipolar disorder (296) 2968 (4.1) 267 (7.3) < 0.001
Major depression (296.2, 296.3) 17,001 (23.6) 1180 (32.2) < 0.001
Paranoid states (297) 1822 (2.5) 90 (2.5) 0.777
Neurotic disorders (300) 59,528 (82.7) 3400 (92.8) < 0.001
Obsessive-compulsive disorders (300.3) 2059 (2.9) 109 (3.0) 0.687
Minor depression (300.4, 309.0, 309.1, 311) 38,542 (53.5) 2382 (65.0) < 0.001
Mild mental retardation (317) 1136 (1.6) 17 (0.5) < 0.001
Other specified mental retardation (318) 949 (1.3) 4 (0.1) < 0.001
Unspecified mental retardation (319) 1266 (1.8) 16 (0.4) < 0.001