Table 2.
Analysis of risk factors for nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) among HIV-infected outpatients
| Characteristic | No. (%) of subjects | P value | ||
|---|---|---|---|---|
| Total (n = 553) | MRSA carriers (n = 19) | Non-MRSA carriers (n = 534) | ||
| Personal history | ||||
| Smoking | 290 (52) | 15 (79) | 275 (51) | 0.020* |
| Alcohol Drinking | 139 (25) | 6 (32) | 133 (25) | 0.590 |
| Hospitalization after HIV diagnosis | 269 (49) | 7 (37) | 262 (49) | 0.354 |
| Recent hospitalization within 1 year | 80 (14) | 5 (26) | 75 (14) | 0.174 |
| Operation history | 16 (3) | 0 (0) | 16 (3) | 1.000 |
| Nurse home | 3 (0.6) | 0 (0) | 3 (0.6) | 1.000 |
| Underlying diseases | ||||
| Hypertension | 59 (11) | 3 (16) | 56 (10) | 0.443 |
| DM | 21 (4) | 1 (5) | 20 (4) | 0.527 |
| Arrhythmia history | 10 (2) | 1 (5) | 9 (2) | 0.297 |
| Angina history | 7 (1) | 0 (0) | 7 (1) | 1.000 |
| Pneumonia history | 26 (5) | 1 (5) | 25 (5) | 0.606 |
| COPD | 6 (1) | 0 (0) | 6 (1) | 1.000 |
| Asthma | 12 (2) | 0 (0) | 12 (2) | 1.000 |
| Tuberculosis | 20 (4) | 1 (5) | 19 (4) | 0.509 |
| HBV carrier | 62 (11) | 2 (11) | 60 (11) | 1.000 |
| HCV carrier | 123 (22) | 10 (53) | 113 (21) | 0.003* |
| Cirrhosis | 3 (0.5) | 1 (5) | 2 (0.4) | 0.100 |
| CKD | 10 (2) | 1 (5) | 9 (2) | 0.297 |
| Cancer | 27 (5) | 5 (26) | 22 (4) | 0.001* |
| Recent infectious diseases (within 3 months) | ||||
| Recent URI | 62 (11) | 2 (11) | 60 (11) | 1.000 |
| Skin infection | 29 (5) | 1 (5) | 28 (5) | 1.000 |
| Unhealed wound | 16 (3) | 1 (5) | 15 (3) | 0.433 |
| UTI | 6 (1) | 0 (0) | 6 (1) | 1.000 |
| Recent treatment (in 3 months) | ||||
| On all catheters | 10 (2) | 1 (5) | 9 (2) | 0.297 |
| Hemodialysis | 2 (0.3) | 1 (5) | 1 (0.2) | 0.068 |
| Antibiotic use in 1 year | 88 (16) | 7 (37) | 81 (15) | 0.020* |
| Laboratory data | ||||
| CD4 count (cells/uL), mean ± SD | 469.16 ± 214.8 | 540.61 + 292.3 | 0.292 | |
| Plasma HIV RNA load (Log10 of copies/ml), mean ± SD | 1.341 ± 2.055 | 0.929 ± 1.660 | 0.293 | |
Abbreviations: DM diabetes mellitus, COPD chronic obstructive pulmonary disease, HBV hepatitis B virus, HCV hepatitis C virus, CKD chronic kidney disease, URI upper respiratory infection, SD standard deviation
*significant difference (p < 0.05)