Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 30;12:32. doi: 10.1186/s13073-020-00731-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 5 — Functional associations of candidate target genes. a DAVID GO analysis of the candidate genes. Plotted are the Bonferroni (BF) corrected p values of the enrichment. The colors of the dots represent the enrichment fold changes. b Circular bar graph of biological functions assigned to the candidate genes by PANTHER GO analysis. c Correlations of candidate genes with tumor metabolites. Plotted are the medians and ranges of Pearson’s correlation coefficients of the candidates with the metabolites of the indicated metabolite classes (Additional file 2: Tab. S4). Only significant (p < 0.05) correlations with median correlation coefficients of ≥ 0.3 are plotted. d Correlation of candidate genes with immuno-oncological processes. An overview of markers descriptive of the processes is given in Additional file 2: Tab. S5. Plotted are the medians and ranges of Pearson’s correlation coefficients if the candidate genes correlated with a coefficient of ≥ 0.3 in at least 25% of samples. e Overview of the final 113 candidates. The color range indicates for each of the plotted parameters the respective values. Exact values can be retrieved from Additional file 2: Tab. S10