Fig. 9.

Protein interaction networks activated by treatment of HepG2 cells with partially purified fractions from MEF 134 extract. a Interconnections of the commonly expressed genes in treated HepG2 cells to a network with interactions in the Biogrid database. Genes from the original 26 gene set are colored green while the genes added as Biogrid interactions are colored red. b Community clustering of the protein interaction network. The Biogrid database was used to construct protein interaction networks using the genes expressed in common in all treatments conditions (V1, V3 and V5) but not in the untreated HepG2 cells