Table 1.
Characteristics of subjects whose liver tissues are analyzed by mRNA-seq and miRNA-seq in GU dataset
| Characteristics | HCC (aN = 30) | ||
|---|---|---|---|
| Age | Mean (SD) | 61.67 (12.2) | |
| Gender | Male | 83.33% | |
| Race | AA | 30% | |
| EA | 37% | ||
| Asian | 33% | ||
| BMI | Mean (SD) | 26.17 (5.4) | |
| Smoking | Yes | 66.67% | |
| No | 33.33% | ||
| Alcohol | Yes | 47% | |
| No | 53% | ||
| HCV Serology | HCV Ab+ | Reactive | 37% |
| HCV Ab+ | Non-Reactive | 60% | |
| HCV Ab+ | Unavailable | 3.33% | |
| HCV RNA+ | Reactive | 16.67% | |
| HCV RNA+ | Non-Reactive | 17% | |
| HCV RNA+ | Unavailable | 63% | |
| HBV Serology | anti HBC+ | Reactive | 10% |
| anti HBC+ | Non-Reactive | 3.33% | |
| anti HBC+ | Unavailable | 87% | |
| HBs Ag+ | Reactive | 17% | |
| HBs Ag+ | Non-Reactive | 70% | |
| HBs Ag+ | Unavailable | 13% | |
| MELD | Mean (SD) | 10.04 (4.5) | |
| MELD < 10 | 56.67% | ||
| AFP (ng/mL) | Median (IQR) | 4.4 (14.05) | |
| Child Pugh Score | Mean (SD) | 6.14 (1.5) | |
| Median (IQR) | 6 (1) | ||
| Child Pugh Class | A | 73% | |
| B | 13.33% | ||
| C | 3.33% | ||
| AST (IU/L) | Median (IQR) | 123 (158) | |
| ALT (IU/L) | Median (IQR) | 117 (152) | |
|
HCC Stage (TNM Staging) |
Stage I | 43% | |
| Stage II | 24% | ||
| Stage III & IV | 33% | ||
aAdjacent normal tissue for the HCC patients are available for this study