Table 1.
Frequency (%) and absolute numbers (cells/ μL) of peripheral blood monocyte subsets in cholangiocarcinoma (CCA) and hepatocellular carcinoma (HCC) patients, both at the time of surgical procedure (T0) and once the patients were recovered from surgery (T1), and in healthy individuals (HG). Frequencies of monocyte subsets are related to the total of monocytes
| CCA N = 8 |
HCC N = 20 |
HG N = 10 |
|||
|---|---|---|---|---|---|
| T0 | T1 | T0 | T1 | ||
| % Monocytes (in whole blood) | 2,4 (1,0-6,6)a,b | 4,9 (2,2-7,0)a | 4,2 (1,5–10)a,b | 5,5 (2,7-9,5)a | 8,2 (5,7–12) |
| Monocytes/μL | 141 (51–330)a | 219 (128–306)a | 329 (135–850)a | 353 (127–733) | 503 (285–757) |
| % Classical | 89 (76–98) | 84 (75–92) | 89 (41–97)a | 90 (74–96)a | 83 (70–88) |
| Classical monocytes/μL | 139 (40–287)a,b | 161 (111–282)a | 318 (129–1361)c | 264 (102–601) | 393 (171–651) |
| % Intermediate | 4,4 (0,3–14) | 7,3 (4,8–12) | 2,5 (0,5–42) | 4,8 (1,7–13) | 5,5 (2,8-8,2) |
| Intermediate monocytes/μL | 6,1 (0,4–36)a | 15 (8,3–17)a | 12 (0,8–194) | 13 (5,8–79) | 23 (17–51) |
| % HLADR+ Intermediate | 32 (23–83) | 44 (33–63) | 45 (16–72)a | 38 (23–80) | 33 (13–56) |
| % HLADR++ Intermediate | 68 (17–77) | 56 (37–67) | 55 (28–84)a | 62 (20–77) | 68 (44–87) |
| % Non-Classical | 6,0 (0,4-7,5)a | 5,0 (1,1–14) | 3,6 (1,0–22)a | 3,5 (0,9–13)a | 11 (5,2–28) |
| Non-classical monocytes/μL | 6,7 (0,6–24)a | 6,5 (1,4–24)a | 15 (2,4–60)a | 13 (2,6–58)a | 61 (26–84) |
Independent-samples Mann-Whitney U test was performed to compare: each group of patients vs healthy group (a); CCA vs HCC (b), The Wilcoxon test was performed to compare T1 vs T0 (c), all of them with a significance level of 0.05 (p < 0.05). The results are given by median (minimum value-maximum value)