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. 2020 Mar 30;10:52. doi: 10.1186/s13578-020-00415-1

Table 4.

Probable list of epigenetic biomarkers targeting all subtypes of breast cancer

S. no. Biomarkers Association with hormonal receptors Breast cancer subtypes
1. APLF TNBC Basal
2. HJURP ER−ve, PR−ve Luminal A
3. MacroH2A.1

TNBC

HER-2

Basal (more), Luminal (less)

HER-2-enriched

4. ɣH2AX

TNBC

HER2−ve

HER2+ve

Basal, HER2 enriched

Luminal A/B (less)

Luminal B (less than TNBC)

5. H2Bub1

ER+ve

TNBC

Luminal A/B (more expression)

Basal (less expression)