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. 2020 Mar 30;20:98. doi: 10.1186/s12935-020-01185-z

Fig. 8.

Fig. 8

miR-122-5p inhibited tumorigenicity in vivo. a Xenograft tumors were obtained from 2 groups of nude mice transfected with mimics control and miR-122-5p mimics respectively. b Tumor growth curve was significantly different between miR-122-5p mimics and mimics control group. c The expression of miR-122-5p in the implanted tumors was explored by miRNA RT-PCR. d The expression of CCNG1 mRNA level was determined by qRT-PCR. e Immunohistochemical staining of CCNG1, Ki-67 and Cleaved caspase 3 in xenograft tumors (*P < 0.05)