Fig. 6.

Mutant KRAS exosomes promote the NET formation and lead to CRC deterioration; a, The adhesion ability of DKs-8 cells; b, The viability of DKs-8 cells detected by CCK-8; c, The invasion and migration ability of DKs-8 cells assessed by Transwell assay (200×); * p < 0.05 compared with the control cells, and # p < 0.05 compared with DKO-1-Exos. The measurement data was expressed as mean ± standard deviation. Data comparisons between groups were performed using one-way analysis of variance, followed by Tukey’s post hoc test. Data analysis at different time points was performed by repeated measurement ANOVA, followed by Bonferroni post hoc test. The experiment repeated three times