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. 2020 Jan 31;53(3):e12769. doi: 10.1111/cpr.12769

Figure 6.

Figure 6

MPP6 is important for the normal levels of ROS, apoptosis, mitochondria and ATP. (A) MPP6 depletion significantly increased ROS level. The dot‐line circles marked the germinal vesicle (GV). (B) Quantification of (A). (C) MPP6 depletion significantly increased annexin V level. The dot‐line circles marked the germinal vesicle (GV). (D) Quantification of (C). (E) ATP level significantly decreased after MPP6 depletion. (F) Mitochondria intensity within the MPP6‐depleted oocyte significantly increased, and mitochondria formed big aggregates after MPP6 depletion. DNA in blue, mitochondria in red. (G) LC3B protein level significantly increased after MPP6 depletion. (H) Quantification of (G). Scale bar, 20 µm. *P < .05