Figure 1.

Relative expression of miR‐29b‐3p was higher in the right ventricular outflow tract (RVOT) of congenital heart disease (CHD) patients. The expression of miR‐29a‐3p (A), miR‐29b‐3p (B), miR‐29b‐5p (C) miR‐29c‐3p (D), miR‐29c‐5p (E) in the RVOT of CHD patients (n = 13) and controls (n = 7) was determined via miRNA stem loop RT‐PCR. MiRNAs were normalized to U6 expression. The expressions of miR‐29a‐3p, miR‐29b‐3p and miR‐29c‐5p were up‐regulated in the RVOT of the CHD patients than the controls. F, The influence of age to the expression of miR‐29 family. Only miR‐29b‐3p expression was not altered as age increased among the 3 up‐regulated miR‐29 family members. The data are presented as the mean ± SEM. Statistical significance is shown as *P < .05 vs controls, **P < .01 vs controls, and ***P < .001 vs controls