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. 2020 Mar 23;13:2411–2419. doi: 10.2147/OTT.S245422

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© 2020 Li et al.

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SPRR3 is up-regulated and correlated with clinical features in NSCLC. (A) SPRR3 expression in NSCLC cell lines was analyzed by qRT-PCR. (B) SPRR3 mRNA in 74 paired tumor samples and adjacent control. (C) SPRR3 in clinical specimens was detected by IHC. (D) SPRR3 expression in a TCGA cohort (n=1129). (E) The relationship between SPRR3 and NSCLC tumor stage. (F) The lymph node metastatic in NSCLC tissues and SPRR3 expression was analyzed. **p<0.01.